SFRP1 Antikörper (N-Term)

Produktnummer ABIN5534287

Produktdetails anti-SFRP1 Antikörper

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Bindungsspezifität: AA 26-55, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1 (SFRP1 Produkte)

Synonyme: FRP antikoerper, FRP-1 antikoerper, FRP1 antikoerper, FrzA antikoerper, SARP2 antikoerper, 2210415K03Rik antikoerper, AW011917 antikoerper, AW107218 antikoerper, AW742929 antikoerper, sFRP-1 antikoerper, CSFRP1 antikoerper, SFRP1 antikoerper, XfrzA antikoerper, frp antikoerper, frp-1 antikoerper, frp1 antikoerper, frzA antikoerper, sarp2 antikoerper, sfrp1 antikoerper, LOC100231868 antikoerper, Srfp1a antikoerper, wu:fd19b09 antikoerper, secreted frizzled related protein 1 antikoerper, secreted frizzled-related protein 1 antikoerper, Secreted frizzled-related protein 1 antikoerper, secreted frizzled-related protein 1a antikoerper, secreted frizzled-related protein 1b antikoerper, SFRP1 antikoerper, Sfrp1 antikoerper, sfrp1 antikoerper, sfrp1a antikoerper, sfrp1b antikoerper

Hintergrund: SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer.

Molekulargewicht: 35 kDa

Gen-ID: 6422

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation