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SFRP1 Antikörper (Secreted Frizzled-Related Protein 1) AA 12 Primary Antibody

SFRP1 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (3 references)
Produktnummer ABIN129592
$658.50
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  • Target Alle SFRP1 Antikörper anzeigen
    SFRP1
    Bindungsspezifität
    • 15
    • 11
    • 9
    • 9
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12
    Reaktivität
    • 75
    • 53
    • 46
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 85
    • 9
    • 8
    • 2
    Kaninchen
    Klonalität
    • 93
    • 11
    Polyklonal
    Konjugat
    • 35
    • 15
    • 9
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SFRP1 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 44
    • 40
    • 13
    • 13
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    SFRP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region of human Sfrp1 protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Sfrp1 by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Huang, Zhang, Teng, Lin, Zheng, Yang, Han: "Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma." in: BMC cancer, Vol. 7, pp. 126, (2007) (PubMed).

    Garcia-Hoyos, Cantalapiedra, Arroyo, Esteve, Rodríguez, Riveiro, Trujillo, Ramos, Bovolenta, Ayuso: "Evaluation of SFRP1 as a candidate for human retinal dystrophies." in: Molecular vision, Vol. 10, pp. 426-31, (2004) (PubMed).

    Han, Amar: "Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2832-40, (2004) (PubMed).

  • Target
    SFRP1
    Andere Bezeichnung
    SFRP1 (SFRP1 Produkte)
    Synonyme
    FRP, FRP-1, FRP1, FrzA, SARP2, 2210415K03Rik, AW011917, AW107218, AW742929, sFRP-1, CSFRP1, SFRP1, XfrzA, frp, frp-1, frp1, frzA, sarp2, sfrp1, LOC100231868, secreted frizzled related protein 1, secreted frizzled-related protein 1, Secreted frizzled-related protein 1, secreted frizzled-related protein 1b, SFRP1, Sfrp1, sfrp1, sfrp1b
    Hintergrund
    Anti-SFRP1 is a Stem Cell Antibody. SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
    Synonyms: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP2 antibody, Secreted Apoptosis-related Protein 2 antibody
    Gen-ID
    6422, 56117838
    UniProt
    Q8N474
    Pathways
    WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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