SFRP1 Antikörper

Produktnummer ABIN7242671

Produktdetails anti-SFRP1 Antikörper

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human SFRP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Andere Bezeichnung: SFRP1 (SFRP1 Produkte)

Synonyme: FRP antikoerper, FRP-1 antikoerper, FRP1 antikoerper, FrzA antikoerper, SARP2 antikoerper, 2210415K03Rik antikoerper, AW011917 antikoerper, AW107218 antikoerper, AW742929 antikoerper, sFRP-1 antikoerper, CSFRP1 antikoerper, SFRP1 antikoerper, XfrzA antikoerper, frp antikoerper, frp-1 antikoerper, frp1 antikoerper, frzA antikoerper, sarp2 antikoerper, sfrp1 antikoerper, LOC100231868 antikoerper, Srfp1a antikoerper, wu:fd19b09 antikoerper, secreted frizzled related protein 1 antikoerper, secreted frizzled-related protein 1 antikoerper, Secreted frizzled-related protein 1 antikoerper, secreted frizzled-related protein 1a antikoerper, secreted frizzled-related protein 1b antikoerper, SFRP1 antikoerper, Sfrp1 antikoerper, sfrp1 antikoerper, sfrp1a antikoerper, sfrp1b antikoerper

Hintergrund: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

NCBI Accession: NP_003003

UniProt: Q8N474

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation