IRF9 Antikörper (N-Term)

Produktnummer ABIN5532927

Produktdetails anti-IRF9 Antikörper

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Bindungsspezifität: AA 75-104, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.28 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IRF9

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Andere Bezeichnung: IRF9 (IRF9 Produkte)

Synonyme: IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper

Hintergrund: IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Molekulargewicht: 44 kDa

Gen-ID: 10379

UniProt: Q00978

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C