PHLPP1 Antikörper (N-Term)

Produktnummer ABIN544485

Produktdetails anti-PHLPP1 Antikörper

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of PHLPP1.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PHLPP1.

Anwendungsinformationen

Applikationshinweise: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PHLPP1 Antikörper (ABIN544485)

Gao, Brognard, Newton: "The phosphatase PHLPP controls the cellular levels of protein kinase C." in: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6300-11, (2008) (PubMed).

Brognard, Sierecki, Gao, Newton: "PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms." in: Molecular cell, Vol. 25, Issue 6, pp. 917-31, (2007) (PubMed).

Gao, Furnari, Newton: "PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth." in: Molecular cell, Vol. 18, Issue 1, pp. 13-24, (2005) (PubMed).

Details zu PHLPP1

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Andere Bezeichnung: PHLPP1 (PHLPP1 Produkte)

Synonyme: PHLPP antikoerper, PLEKHE1 antikoerper, SCOP antikoerper, AI836256 antikoerper, Phlpp antikoerper, Plekhe1 antikoerper, mKIAA0606 antikoerper, Scop antikoerper, PH domain and leucine rich repeat protein phosphatase 1 antikoerper, PHLPP1 antikoerper, phlpp1 antikoerper, Phlpp1 antikoerper

Gen-ID: 23239

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung