MDM2 Antikörper (pThr218)

Produktnummer ABIN542667

Produktdetails anti-MDM2 Antikörper

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Bindungsspezifität: pThr218

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDM2 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of MDM2.

Kreuzreaktivität: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T218 of human MDM2.

Anwendungsinformationen

Applikationshinweise: Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-MDM2 Antikörper (ABIN542667)

Mantesso, Loducca, Bendit, Garicochea, Nunes, de Araújo: "Mdm2 mRNA expression in salivary gland tumour cell lines." in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 33, Issue 2, pp. 96-101, (2004) (PubMed).

Schon, Friedler, Freund, Fersht: "Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes." in: Journal of molecular biology, Vol. 336, Issue 1, pp. 197-202, (2004) (PubMed).

Burch, Scott, Pohler, Meek, Hupp: "Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1." in: Journal of molecular biology, Vol. 337, Issue 1, pp. 115-28, (2004) (PubMed).

Details zu MDM2

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Andere Bezeichnung: MDM2 (MDM2 Produkte)

Synonyme: ACTFS antikoerper, HDMX antikoerper, hdm2 antikoerper, zgc:109834 antikoerper, 1700007J15Rik antikoerper, AA415488 antikoerper, Mdm-2 antikoerper, MDM2 proto-oncogene antikoerper, MDM2 proto-oncogene S homeolog antikoerper, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antikoerper, MDM2 oncogene, E3 ubiquitin protein ligase antikoerper, transformed mouse 3T3 cell double minute 2 antikoerper, MDM2 antikoerper, mdm2.S antikoerper, Mdm2 antikoerper, mdm2 antikoerper

Gen-ID: 4193

Pathways: p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie, Ubiquitin Proteasome Pathway