CD11c Antikörper (AA 620-835)

Produktnummer ABIN5027081

Produktdetails anti-CD11c Antikörper

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Bindungsspezifität: AA 620-835

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11c Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.

Klon: ABM4C58

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: IHC: 5-10 μg/mL FACS: 0.5 - 1 μg//10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Andere Bezeichnung: CD11c (ITGAX Produkte)

Synonyme: CD11C antikoerper, SLEB6 antikoerper, RGD1561123 antikoerper, AI449405 antikoerper, Cd11c antikoerper, Cr4 antikoerper, N418 antikoerper, integrin subunit alpha X antikoerper, integrin alpha X antikoerper, ITGAX antikoerper, Itgax antikoerper

Hintergrund: CD11c/CD18 ( p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.

Gen-ID: 3687

UniProt: P20702

Pathways: Komplementsystem, Activated T Cell Proliferation, Integrin Complex