TNFRSF13C Antikörper (AA 1-30)

Produktnummer ABIN3029360

Produktdetails anti-TNFRSF13C Antikörper

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Bindungsspezifität: AA 1-30

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF13C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this BAFF Receptor antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the BAFF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the BAFF Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Andere Bezeichnung: BAFF Receptor (TNFRSF13C Produkte)

Synonyme: RGD1560810 antikoerper, TNFRSF13C antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, TNF receptor superfamily member 13C antikoerper, uncharacterized LOC746611 antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, TNFRSF13C antikoerper, Tnfrsf13c antikoerper, LOC746611 antikoerper

Hintergrund: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

UniProt: Q96RJ3

Pathways: NF-kappaB Signalweg