Caspase 1 Antikörper (Internal Region)
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- Target Alle Caspase 1 (CASP1) Antikörper anzeigen
- Caspase 1 (CASP1)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- Caspase-1 is a protein encoded by the CASP1 gene which is approximately 45,1 kDa. Caspase-1 is localised to the cytoplasm. It is involved in amyotrophic lateral sclerosis, toll-like receptor signalling pathways, p53 signalling and the TNFR1 pathway. This protein falls under the the cysteine-aspartic acid protease family. upon activation It plays a central role in the execution-phase of cell apoptosis. These enzymes can be divided into initiators and effectors. The initiator isoforms are activated by, and interact with, upstream adaptor molecules. Caspase-1 is expressed mainly in the spleen and lung. Mutations in the CASP1 gene may result in shigellosis and cowpox. STJ98574 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Caspase-1.
- Spezifität
- Caspase-1 Polyclonal Antibody detects endogenous levels of Caspase-1
- Produktmerkmale
- Rabbit Polyclonal to Caspase-1.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from Caspase-1
- Isotyp
- IgG
- Top Product
- Discover our top product CASP1 Primärantikörper
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- Applikationshinweise
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WB 1:500-2000
ELISA 1:10000-20000 - Kommentare
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Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- Caspase 1 (CASP1)
- Andere Bezeichnung
- Caspase-1 (CASP1 Produkte)
- Synonyme
- ICE antikoerper, IL1BC antikoerper, P45 antikoerper, Il1bc antikoerper, Ice antikoerper, CASP1 antikoerper, CG5370 antikoerper, DCP-1 antikoerper, DCP1 antikoerper, Dcp1 antikoerper, Dmel\\CG5370 antikoerper, ccp1 antikoerper, dcp-1 antikoerper, dcp1 antikoerper, l(2)01862 antikoerper, l(2)02132 antikoerper, caspase 1 antikoerper, caspase 1, apoptosis-related cysteine peptidase antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, Death caspase-1 antikoerper, caspase-1 antikoerper, caspase antikoerper, caspase recruitment domain-containing protein 16 antikoerper, caspase 4 antikoerper, CASP1 antikoerper, Casp1 antikoerper, CASP4 antikoerper, Dcp-1 antikoerper, Caspase1 antikoerper, LOC5564196 antikoerper, LOC451519 antikoerper
- Gen-ID
- 834
- UniProt
- P29466
- Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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