Caspase 1 Produkte
(Caspase 1 (CASP1))
Kategorien
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
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Ausgewählte Caspase 1 Kategorien
Caspase 1 Antikörper
High quality antibodies with extensive validation data.
Caspase 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Caspase 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Caspase 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7438055
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7433831
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7437506
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Caspase 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (5)
Kat. Nr.
ABIN6574284
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6954410
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965449
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Caspase 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122160
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122161
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348088
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Caspase 1 Produkten
: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).: "Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing." in: Frontiers in bioengineering and biotechnology, Vol. 9, pp. 690409, (2021) (PubMed).
: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).
: "HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 61-80, (2020) (PubMed).
: "Serum Caspase-1 levels in women with polycystic ovary syndrome." in: Taiwanese journal of obstetrics & gynecology, Vol. 59, Issue 2, pp. 207-210, (2020) (PubMed).
: "Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways." in: Chemico-biological interactions, Vol. 297, pp. 25-33, (2019) (PubMed).
: "Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. ..." in: Immunity, Vol. 49, Issue 1, pp. 42-55.e6, (2019) (PubMed).
: "Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome." in: Mucosal immunology, Vol. 12, Issue 4, pp. 862-873, (2019) (PubMed).
: "Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats." in: International journal of molecular sciences, Vol. 19, Issue 9, (2019) (PubMed).
: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
Synonyme und alternative Namen zu Caspase 1
caspase 1 (CASP1), caspase 1 (Casp1), caspase 1, apoptosis-related cysteine peptidase (CASP1), caspase 4, apoptosis-related cysteine peptidase (CASP4), Death caspase-1 (Dcp-1), caspase-1 (Caspase1), caspase (LOC5564196), caspase recruitment domain-containing protein 16 (LOC451519), caspase-1 (CASP1), caspase 4 (CASP4), CASP1, ccp1, CG5370, DCP-1, dcp-1, DCP1, Dcp1, dcp1, Dmel\\CG5370, ICE, Ice, IL1BC, Il1bc, l(2)01862, l(2)02132, P45Bezeichner auf Proteinebene für Caspase 1
- CASP1 nirs variant 1
- IL-1 beta-converting enzyme
- IL1B-convertase
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase-1
- interleukin 1, beta, convertase
- interleukin 1-B converting enzyme
- CASP-1
- IL-1B converting enzyme
- IL-1BC
- interleukin 1 beta-converting enzyme
- interleukin-1 beta convertase
- interleukin-1 beta-converting enzyme
- p45
- Interleukin 1beta converting enzyme
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- ICE
- interleukin-1 beta converting enzyme
- caspase-1/caspase-4 hybrid
- CG5370-PA
- Dcp-1-PA
- caspase
- caspase 1
- death caspase-1
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