CASP5 Produkte
(Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
Kategorien
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010].
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Ausgewählte CASP5 Kategorien
CASP5 Antikörper
High quality antibodies with extensive validation data.
CASP5 ELISA Kits
Reliable ELISA kits for a wide range of species.
CASP5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CASP5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IP
Validierungen
- (4)
Kat. Nr.
ABIN7432568
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN654898
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN3030309
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene CASP5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965469
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954421
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CASP5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348109
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3090739
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3090740
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CASP5 Produkten
: "Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy. ..." in: The Journal of allergy and clinical immunology, (2019) (PubMed).: "Differential Effects of Dexamethasone and Doxycycline on Inflammation and MMP Production in Murine Alkali-Burned Corneas Associated with Dry Eye." in: The ocular surface, Vol. 14, Issue 2, pp. 242-54, (2016) (PubMed).
: "Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas." in: Investigative ophthalmology & visual science, Vol. 56, Issue 8, pp. 4908-18, (2015) (PubMed).
: "Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens." in: Cell host & microbe, Vol. 16, Issue 2, pp. 249-56, (2014) (PubMed).
: "Expression and functional roles of caspase-5 in inflammatory responses of human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 12, pp. 8646-56, (2011) (PubMed).
: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).
: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).
: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).
: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, (2004) (PubMed).
: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, (2003) (PubMed).
Synonyme und alternative Namen zu CASP5
caspase 5 (CASP5), caspase-5 (LOC100437308), CASP5, ICE(rel)III, ICEREL-III, ICH-3Bezeichner auf Proteinebene für CASP5
- CASP-5
- ICE(rel)-III
- TY protease
- caspase 5, apoptosis-related cysteine protease
- caspase-5
- protease ICH-3
- protease TY
- caspase 5
- caspase 5, apoptosis-related cysteine peptidase
- caspase-5-like
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