Caspase 12 (Gene/pseudogene) Produkte
(Caspase 12 (Gene/pseudogene) (CASP12))
Kategorien
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].
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Ausgewählte Caspase 12 (Gene/pseudogene) Kategorien
Caspase 12 (Gene/pseudogene) Antikörper
High quality antibodies with extensive validation data.
Caspase 12 (Gene/pseudogene) ELISA Kits
Reliable ELISA kits for a wide range of species.
Caspase 12 (Gene/pseudogene) Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Caspase 12 (Gene/pseudogene) Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (10)
Kat. Nr.
ABIN7442993
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7440263
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validierungen
- (8)
- (5)
Kat. Nr.
ABIN737736
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Caspase 12 (Gene/pseudogene) ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965454
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965453
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965452
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Caspase 12 (Gene/pseudogene) Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3090819
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7415872
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422757
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Caspase 12 (Gene/pseudogene) Produkten
: "Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD." in: Life sciences, Vol. 209, pp. 455-465, (2018) (PubMed).: "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, (2017) (PubMed).
: "Gypenoside Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting Cardiomyocytes Apoptosis via Inhibition of CHOP Pathway and Activation of PI3K/Akt Pathway In Vivo and In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 1, pp. 123-36, (2016) (PubMed).
: "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, (2016) (PubMed).
: "Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study." in: Biochemical pharmacology, Vol. 95, Issue 3, pp. 145-55, (2015) (PubMed).
: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).
: "Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 8, pp. 9256-63, (2015) (PubMed).
: "Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome." in: Gene, Vol. 545, Issue 1, pp. 156-62, (2014) (PubMed).
: "Zinc chloride inhibits human lens epithelial cell migration and proliferation involved in TGF-β1 and TNF-α signaling pathways in HLE B-3 cells." in: Biological trace element research, Vol. 159, Issue 1-3, pp. 425-33, (2014) (PubMed).
: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).
Synonyme und alternative Namen zu Caspase 12 (Gene/pseudogene)
caspase 12 (Casp12), caspase 12 (CASP12), caspase 12 (gene/pseudogene) (CASP12), CASP-12, CASP12P1, Caspase-12Bezeichner auf Proteinebene für Caspase 12 (Gene/pseudogene)
- CASP-12
- caspase-12
- caspase 12 pseudogene 1
- inactive caspase-12
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