ROR1 Antikörper

Produktnummer ABIN462403

Produktdetails anti-ROR1 Antikörper

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ROR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human ROR1. This antibody is expected to recognize isoform 1 (NP_005003.2) only.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Lizard (93%) Turkey, Chicken (87%) Platypus (80%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-GNKSQKPYKIDSKQA from the C-terminus (near) of human ROR1 (NP_005003.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Lizard (93%), Turkey, Chicken (87%), Platypus (80%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3 - 6 μg/mL), Peptide-ELISA

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3-6 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ROR1

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Andere Bezeichnung: ROR1 (ROR1 Produkte)

Synonyme: NTRKR1 antikoerper, dJ537F10.1 antikoerper, 2810404D04Rik antikoerper, Ntrkr1 antikoerper, mRor1 antikoerper, RGD1559469 antikoerper, ROR1 antikoerper, fi34e02 antikoerper, si:dkey-209n16.1 antikoerper, wu:fi34e02 antikoerper, receptor tyrosine kinase like orphan receptor 1 antikoerper, receptor tyrosine kinase-like orphan receptor 1 antikoerper, ROR1 antikoerper, Ror1 antikoerper, ror1 antikoerper

Hintergrund: Name/Gene ID: ROR1
Subfamily: Trk/Ror
Family: Protein Kinase

Synonyms: ROR1, DJ537F10.1, NTRKR1, Protein tyrosine kinase t-ror1

Gen-ID: 4919

NCBI Accession: NP_005003

UniProt: Q01973

Pathways: RTK Signalweg, WNT Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha