ROR1 Produkte
(Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
Kategorien
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte ROR1 Kategorien
ROR1 Antikörper
High quality antibodies with extensive validation data.
ROR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ROR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ROR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7439615
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN392043
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (8)
Kat. Nr.
ABIN3032439
Menge
0.2 mL
Datenblatt
Datenblatt
Empfohlene ROR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959062
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4886267
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4884374
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ROR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validierungen
- (5)
Kat. Nr.
ABIN7275532
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275530
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus, Human, Rhesus Monkey
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275527
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ROR1 Produkten
: "ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma." in: Oncogene, Vol. 38, Issue 26, pp. 5142-5157, (2019) (PubMed).: "Interaction between ROR1 and MuSK activation complex in myogenic cells." in: FEBS letters, Vol. 592, Issue 3, pp. 434-445, (2019) (PubMed).
: "Antibody-drug conjugate T-DM1 treatment for HER2+ breast cancer induces ROR1 and confers resistance through activation of Hippo transcriptional coactivator YAP1." in: EBioMedicine, Vol. 43, pp. 211-224, (2019) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
: "Silencing ROR1 and ROR2 inhibits invasion and adhesion in an organotypic model of ovarian cancer metastasis." in: Oncotarget, Vol. 8, Issue 68, pp. 112727-112738, (2018) (PubMed).
: "Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL." in: Oncogene, Vol. 37, Issue 38, pp. 5221-5232, (2018) (PubMed).
: "A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198038, (2018) (PubMed).
: "ROR1 and ROR2 play distinct and opposing roles in endometrial cancer." in: Gynecologic oncology, Vol. 148, Issue 3, pp. 576-584, (2018) (PubMed).
: "ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1." in: Nature communications, Vol. 7, pp. 10060, (2016) (PubMed).
: "Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).
Synonyme und alternative Namen zu ROR1
receptor tyrosine kinase like orphan receptor 1 (ROR1), receptor tyrosine kinase-like orphan receptor 1 (Ror1), receptor tyrosine kinase like orphan receptor 1 (Ror1), receptor tyrosine kinase-like orphan receptor 1 (ror1), 2810404D04Rik, dJ537F10.1, fi34e02, mRor1, NTRKR1, Ntrkr1, RGD1559469, ROR1, si:dkey-209n16.1, wu:fi34e02Bezeichner auf Proteinebene für ROR1
- neurotrophic tyrosine kinase, receptor-related 1
- tyrosine-protein kinase transmembrane receptor ROR1
- neurotrophic tyrosine kinase, receptor related 1
- tyrosine kinase orphan receptor 1
- receptor tyrosine kinase-like orphan receptor 1
- tyrosine-protein kinase transmembrane receptor ROR1-like
- inactive tyrosine-protein kinase transmembrane receptor ROR1
Sie sind hier:
