RP1 Produkte
(Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
Kategorien
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq, Sep 2010].
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Ausgewählte RP1 Kategorien
RP1 Antikörper
High quality antibodies with extensive validation data.
Empfohlene RP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
IF (cc), IF (p), IHC (fro), IHC (p), ELISA, ICC
Validierungen
Kat. Nr.
ABIN1386374
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC (fro), IHC (p), ELISA
Validierungen
Kat. Nr.
ABIN1388857
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IF (cc), IF (p)
Validierungen
Kat. Nr.
ABIN5008105
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422604
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422817
Menge
100 μg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu RP1
RP1, axonemal microtubule associated L homeolog (rp1.L), RP1, axonemal microtubule associated (RP1), retinitis pigmentosa 1 (autosomal dominant) (rp1), uncharacterized LOC100355685 (LOC100355685), RP1, axonemal microtubule associated (Rp1), retinitis pigmentosa 1 (human) (Rp1), Dcdc3, DCDC4A, mG145, MGC83581, orp1, ORP1, Orp1, Rp1hBezeichner auf Proteinebene für RP1
- retinitis pigmentosa 1 (autosomal dominant)
- retinitis pigmentosa RP1 protein
- oxygen-regulated protein 1-like
- oxygen-regulated protein 1
- retinitis pigmentosa 1 protein
- retinitis pigmentosa RP1 protein homolog
- retinitis pigmentosa 1 homolog
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