MEK2 Antikörper (AA 262-292)

Produktnummer ABIN392485

Produktdetails anti-MEK2 Antikörper

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Bindungsspezifität: AA 262-292

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This MEK2 (MAP2K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-292 amino acids from the Central region of human MEK2 (MAP2K2).

Klon: RB3597

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Andere Bezeichnung: MEK2 (MAP2K2) (MAP2K2 Produkte)

Synonyme: CFC4 antikoerper, MAPKK2 antikoerper, MEK2 antikoerper, MKK2 antikoerper, PRKMK2 antikoerper, AA589381 antikoerper, MK2 antikoerper, Prkmk2 antikoerper, ATMKK2 antikoerper, F27B13.50 antikoerper, F27B13_50 antikoerper, MAP KINASE KINASE 1 antikoerper, MAP kinase kinase 2 antikoerper, MK1 antikoerper, map2k2 antikoerper, wu:fa56c06 antikoerper, zgc:123171 antikoerper, zgc:172250 antikoerper, mitogen-activated protein kinase kinase 2 antikoerper, mitogen activated protein kinase kinase 2 antikoerper, MAP kinase kinase 2 antikoerper, mitogen-activated protein kinase kinase 2a antikoerper, mitogen-activated protein kinase kinase 2b antikoerper, MAP2K2 antikoerper, Map2k2 antikoerper, MKK2 antikoerper, map2k2a antikoerper, map2k2b antikoerper

Hintergrund: MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.

Molekulargewicht: 44424

Gen-ID: 5605

NCBI Accession: NP_109587

UniProt: P36507

Pathways: MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling