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CD14 Antikörper (AA 33-44)

CD14 Reaktivität: Human FACS, Agon Wirt: Maus Monoclonal biG4 unconjugated
Produktnummer ABIN343171
  • Target Alle CD14 Antikörper anzeigen
    CD14
    Bindungsspezifität
    • 16
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-44
    Reaktivität
    • 268
    • 55
    • 32
    • 30
    • 29
    • 28
    • 25
    • 24
    • 24
    • 18
    • 17
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 224
    • 64
    • 25
    • 3
    • 1
    Maus
    Klonalität
    • 253
    • 64
    Monoklonal
    Konjugat
    • 128
    • 30
    • 24
    • 18
    • 15
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD14 Antikörper ist unkonjugiert
    Applikation
    • 223
    • 104
    • 64
    • 59
    • 54
    • 50
    • 22
    • 22
    • 21
    • 14
    • 14
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Agonist (Agon)
    Spezifität
    Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.
    Aufreinigung
    Protein A affinity column
    Immunogen
    human Monocytes
    Klon
    BiG4
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD14 Primärantikörper
  • Applikationshinweise
    no significant inhibition of LPS binding to CD14
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with bidistilled water
    Konzentration
    1 mg/mL
    Buffer
    PBS, pH 7.8
    Konservierungsmittel
    Without preservative
    Lagerung
    -20 °C,-80 °C
  • Target
    CD14
    Andere Bezeichnung
    CD14 (CD14 Produkte)
    Synonyme
    CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
    Hintergrund
    Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    Molekulargewicht
    ~50kDa
    Gen-ID
    929
    NCBI Accession
    NP_000582
    UniProt
    P08571
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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