Caspase 9 Antikörper (C-Term)
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- Target Alle Caspase 9 (CASP9) Antikörper anzeigen
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Cysteine-requiring Aspartate Protease-9, iCE-like apoptotic protease 6,Apoptotic protease Mch-6, Apoptotic protease-activating factor 3,Endothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, also known as lysophospholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca2+]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.
- Aufreinigung
- Ammonium Sulfate Precipitation
- Immunogen
- Synthetic peptide derived from the C terminal of the EDG2 receptor.
- Isotyp
- IgG
- Top Product
- Discover our top product CASP9 Primärantikörper
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- Applikationshinweise
- For Western blotting, starting dilution of 5-10 μg/mL is recommended. Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Target
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Andere Bezeichnung
- Caspase-9 (CASP9 Produkte)
- Synonyme
- CASP9 antikoerper, AI115399 antikoerper, APAF-3 antikoerper, AW493809 antikoerper, CASP-9 antikoerper, Caspase-9 antikoerper, ICE-LAP6 antikoerper, Mch6 antikoerper, Apaf3 antikoerper, Casp-9-CTD antikoerper, Casp9_v1 antikoerper, Ice-Lap6 antikoerper, APAF3 antikoerper, MCH6 antikoerper, PPP1R56 antikoerper, caspase 9 antikoerper, CASP9 antikoerper, Casp9 antikoerper
- UniProt
- Q92633
- Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
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