DR3/LARD Antikörper (N-Term)

Produktnummer ABIN3042955

Produktdetails anti-DR3/LARD Antikörper

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Bindungsspezifität: AA 73-94, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR3/LARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25(TNFRSF25) detection. Tested with WB in Human.

Sequenz: CPQDTFLAWE NHHNSECARC QA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25(TNFRSF25) detection. Tested with WB in Human.
Gene Name: tumor necrosis factor receptor superfamily, member 25
Protein Name: Tumor necrosis factor receptor superfamily member 25

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DR3(73-94aa CPQDTFLAWENHHNSECARCQA).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TNFRSF25 is approximately 3 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: TNFRSF25 (TNFRSF25 Produkte)

Synonyme: APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper

Hintergrund: TNFRSF25(Tumor Necrosis Factor Receptor Superfamily Member 25), also known as LARD, APO3, DR3 or TNFR25, is a protein that in humans is encoded by the TNFRSF25 gene. Members of the mammalian tumor necrosis factor receptor(TNFR) family are cell-surface proteins that interact with a corresponding TNF-related ligand family. By fluorescence in situ hybridization, Marsters et al.(1996) mapped the Apo3 gene to 1p36.3. Marsters et al.(1996) showed that ectopic expression of Apo3 in mammalian cells triggered apoptosis and activated the transcription factor NF-kappa-B. They suggested that, like TNFR1, Apo3 may regulate distinct signaling pathways in different cellular contexts.

Synonyms: Apo 3 antibody|Apo-3 antibody|Apo3 antibody|Apoptosis inducing receptor AIR antibody|Apoptosis inducing receptor antibody|Apoptosis mediating receptor antibody|Apoptosis mediating receptor DR 3 antibody|Apoptosis mediating receptor DR3 antibody|Apoptosis mediating receptor TRAMP antibody|Apoptosis-inducing receptor AIR antibody|Apoptosis-mediating receptor DR3 antibody|Apoptosis-mediating receptor TRAMP antibody|DDR 3 antibody|DDR3 antibody|Death domain receptor 3 antibody|Death Receptor 3 antibody|Death receptor beta antibody|DR 3 antibody|LARD antibody|Lymphocyte associated receptor of death antibody|Lymphocyte-associated receptor of death antibody|Protein WSL antibody|Protein WSL-1 antibody|TNFRSF 12 antibody|TNFRSF 25 antibody|TNFRSF12 antibody|TNFRSF25 antibody|TNR25_HUMAN antibody|TR 3 antibody|TR3 antibody|TRAMP antibody|Translocating chain association membrane protein antibody|Tumor necrosis factor receptor superfamily member 12 antibody|Tumor necrosis factor receptor superfamily member 25 antibody|WSL 1 antibody|WSL antibody|WSL LR antibody|WSL protein antibody|WSL1 antibody|WSL1 protein antibody|WSLLR antibody

UniProt: Q93038

Pathways: Apoptose