NPM1 Antikörper (AA 1-294)

Produktnummer ABIN3032073

Produktdetails anti-NPM1 Antikörper

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Bindungsspezifität: AA 1-294

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-294) was used as the immunogen for this Nucleophosmin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Nucleophosmin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Nucleophosmin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Andere Bezeichnung: Nucleophosmin (NPM1 Produkte)

Synonyme: B23 antikoerper, NPM antikoerper, NO38 antikoerper, Npm antikoerper, B23NP antikoerper, npm4 antikoerper, npm antikoerper, CG7917 antikoerper, CRP1 antikoerper, Crp1 antikoerper, Dmel\\CG7917 antikoerper, dNLP antikoerper, dNLP-S antikoerper, p22 antikoerper, npm1 antikoerper, sb:cb487 antikoerper, nucleophosmin 1 antikoerper, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog antikoerper, nucleophosmin 1b antikoerper, Nucleophosmin antikoerper, nucleophosmin antikoerper, nucleophosmin (nucleolar phosphoprotein B23, numatrin) antikoerper, Nucleoplasmin antikoerper, nucleophosmin 1a antikoerper, NPM1 antikoerper, Npm1 antikoerper, npm1.L antikoerper, npm1b antikoerper, npm antikoerper, Nlp antikoerper, npm1a antikoerper

Hintergrund: NPM1 or NPM (Nucleophosmin/Nucleoplasmin family member1), also known as Nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. Chan et al. (1989) found that NPM is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in Nucleophosmin protein level. They stated that the protein is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that Nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.

Gen-ID: 4869

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly