NPM1 Antikörper (AA 7-33)
Kurzübersicht für NPM1 Antikörper (AA 7-33) (ABIN3032075)
Target
Alle NPM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 7-33
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Verwendungszweck
- NPM1 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 7-33 from the human protein was used as the immunogen for this NPM1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the NPM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the NPM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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Andere Bezeichnung
- NPM1
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Hintergrund
- Nucleophosmin/NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
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UniProt
- P06748
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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