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JAK2 Antikörper (pTyr1007)

JAK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3020271
  • Target Alle JAK2 Antikörper anzeigen
    JAK2 (Janus Kinase 2 (JAK2))
    Bindungsspezifität
    • 31
    • 28
    • 16
    • 16
    • 12
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1007
    Reaktivität
    • 165
    • 99
    • 94
    • 18
    • 18
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 167
    • 6
    • 2
    Kaninchen
    Klonalität
    • 156
    • 19
    Polyklonal
    Konjugat
    • 88
    • 15
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser JAK2 Antikörper ist unkonjugiert
    Applikation
    • 128
    • 79
    • 60
    • 52
    • 29
    • 27
    • 23
    • 22
    • 16
    • 10
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Phosphorylated Antibodies
    Immunogen
    A phospho specific peptide corresponding to residues surrounding Y1007 of human Phospho-JAK2-Y1007
    Isotyp
    IgG
    Top Product
    Discover our top product JAK2 Primärantikörper
  • Applikationshinweise
    WB,1:200 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Yang, Li, Shao, Wei, Wang, Li, Xu: "Exogenous spermine ameliorates high glucose-induced cardiomyocytic apoptosis via decreasing reactive oxygen species accumulation through inhibiting p38/JNK and JAK2 pathways." in: International journal of clinical and experimental pathology, Vol. 8, Issue 12, pp. 15537-49, (2016) (PubMed).

  • Target
    JAK2 (Janus Kinase 2 (JAK2))
    Andere Bezeichnung
    JAK2 (JAK2 Produkte)
    Synonyme
    JAK2bCA antikoerper, jak2 antikoerper, JTK10 antikoerper, THCYT3 antikoerper, AI504024 antikoerper, C81284 antikoerper, Fd17 antikoerper, JAK-2 antikoerper, Janus kinase 2b antikoerper, Janus kinase 2 antikoerper, jak2b antikoerper, JAK2 antikoerper, Jak2 antikoerper
    Hintergrund
    This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.,JAK2,JTK10,THCYT3,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Cell cycle inhibitors,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Protein phosphorylation,JAK2
    Molekulargewicht
    130 kDa
    Gen-ID
    3717
    UniProt
    O60674
    Pathways
    JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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