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JAK2 Antikörper (C-Term)

Name: JAK2 Antikörper (C-Term)
SKU: ABIN387982
Price: 445.5 EUR
Availability: InStock

JAK2 Reaktivität: Human, Maus WB, FACS, IF Wirt: Kaninchen Polyclonal RB02956 unconjugated

The anti-JAK2 Pab (ABIN387982 and ABIN2844820) is used in Western blot to detect JAK2 in mouse thymus tissue lysate.

JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) flow cytometric analysis of K562 cells (right histogram) compared to a negative control (PBS alone) (left histogram).

FACS

Confocal immunofluorescent analysis of JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN387982

Datenblatt (PDF)

Target Alle JAK2 Antikörper anzeigen

JAK2 (Janus Kinase 2 (JAK2))
Bindungsspezifität
37

34

16

16

12

10

7

7

6

6

6

6

6

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1101-1132, C-Term
Reaktivität
171

100

97

18

18

3

2

2

1
Human, Maus
Wirt
173

6

2
Kaninchen
Passende Sekundärantikörper
Klonalität
158

23
Polyklonal
Konjugat
91

15

9

6

6

6

6

6

6

6

5

3

3

3

3

3

3

1
Dieser JAK2 Antikörper ist unkonjugiert
Applikation
129

81

62

56

29

27

25

21

17

12

10

5

4

2

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.

Klon

RB02956

Isotyp

Ig Fraction

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anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 Reaktivität: Human, Ratte, Maus, Kaninchen, Zebrafisch (Danio rerio) WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
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JAK2 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 5C12C9 unconjugated

anti-Janus Kinase 2 (JAK2) antibody
JAK2 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 508-800) antibody
JAK2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr931) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr221) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Monoclonal 1A4 unconjugated Recombinant Antibody

anti-Janus Kinase 2 (JAK2) (C-Term) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Kanda, Watanabe: "Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes." in: Endocrinology, Vol. 148, Issue 5, pp. 2317-25, (2007) (PubMed).
Target

JAK2 (Janus Kinase 2 (JAK2))

Andere Bezeichnung

JAK2 (JAK2 Produkte)

Synonyme

JAK2bCA antikoerper, jak2 antikoerper, JTK10 antikoerper, THCYT3 antikoerper, AI504024 antikoerper, C81284 antikoerper, Fd17 antikoerper, JAK-2 antikoerper, Janus kinase 2b antikoerper, Janus kinase 2 antikoerper, jak2b antikoerper, JAK2 antikoerper, Jak2 antikoerper

Hintergrund

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Molekulargewicht

130674

Gen-ID

3717

NCBI Accession

NP_004963

UniProt

O60674

Pathways

JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response