CD11c Antikörper (N-Term)
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- Target Alle CD11c (ITGAX) Antikörper anzeigen
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD11c Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
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Rabbit Polyclonal antibody to CD11c
CD11c antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human Integrin alphaX. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ITGAX Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Kommentare
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Positive Control: H1299 , HeLaS3 , HepG2 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- Andere Bezeichnung
- CD11c (ITGAX Produkte)
- Hintergrund
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This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Cellular Localization: Membrane, Single-pass type I membrane protein - Molekulargewicht
- 128 kDa
- Gen-ID
- 3687
- Pathways
- Komplementsystem, Activated T Cell Proliferation, Integrin Complex
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