TNFSF9 Antikörper (C-Term)
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- Target Alle TNFSF9 Antikörper anzeigen
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TNFSF9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TNFSF9. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product TNFSF9 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 254 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Andere Bezeichnung
- TNFSF9 (TNFSF9 Produkte)
- Synonyme
- TNFSF9 antikoerper, 4-1BB-L antikoerper, 4-1BBL antikoerper, AI848817 antikoerper, Cd137l antikoerper, Ly63l antikoerper, CD137L antikoerper, TNF superfamily member 9 antikoerper, tumor necrosis factor (ligand) superfamily, member 9 antikoerper, Tnfsf9 antikoerper, LOC476729 antikoerper, TNFSF9 antikoerper
- Hintergrund
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Alias Symbols: 4-1BB-L, CD137L
Protein Interaction Partner: TIRAP, TLR4, IRAK2, UBC, TNFRSF9, TRAF2, TRAF1,
Protein Size: 254 - Molekulargewicht
- 28 kDa
- Gen-ID
- 8744
- NCBI Accession
- NM_003811, NP_003802
- UniProt
- P41273
- Pathways
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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