NFATC1 Antikörper (N-Term)
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- Target Alle NFATC1 Antikörper anzeigen
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Meerschweinchen, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFATC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HVSFYVCNGK RKRSQYQRFT YLPANVPIIK TEPTDDYEPA PTCGPVSQGL
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NFATC1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1
- Top Product
- Discover our top product NFATC1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 353 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Andere Bezeichnung
- NFATC1 (NFATC1 Produkte)
- Synonyme
- nf-atc antikoerper, nfat2 antikoerper, nfatc antikoerper, si:ch211-198c22.2 antikoerper, NFATC1 antikoerper, 2210017P03Rik antikoerper, AI449492 antikoerper, AV076380 antikoerper, NF-ATc antikoerper, NFAT2 antikoerper, NFATc antikoerper, Nfatcb antikoerper, NF-ATC antikoerper, NF-ATc1 antikoerper, NFAT antikoerper, NFATmac antikoerper, nuclear factor of activated T-cells 1 antikoerper, nuclear factor of activated T-cells 1 L homeolog antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antikoerper, NFATC1 antikoerper, nfatc1.L antikoerper, nfatc1 antikoerper, Nfatc1 antikoerper
- Hintergrund
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: YWHAQ, OGT, PML, GZF1, FOXP3, HDAC4, PIAS1, SUMO1, UBE2I, RPS6KB1, RPS6KA3, HDAC2, HDAC1, HNRNPA1, TUBA1A, KPNB1, HDAC5, KAT2B, EP300, PARP1, HDAC3, PPP3R1, MAPK14, GNB2L1, PRKCA, SPI1, PIM1, EGR2, EGR1,
Protein Size: 353 - Molekulargewicht
- 38 kDa
- Gen-ID
- 4772
- NCBI Accession
- NM_172388, NP_765976
- UniProt
- O95644
- Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung
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