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LY9 Antikörper

CD229 Reaktivität: Human WB, FACS, IP, ICC, Func Wirt: Maus Monoclonal HLy9-25 unconjugated
Produktnummer ABIN2749218
  • Target Alle LY9 (CD229) Antikörper anzeigen
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    Reaktivität
    • 42
    • 6
    • 3
    Human
    Wirt
    • 27
    • 16
    • 2
    Maus
    Klonalität
    • 28
    • 17
    Monoklonal
    Konjugat
    • 19
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY9 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 13
    • 13
    • 10
    • 10
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
    Spezifität
    The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Endotoxin-Niveau
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Immunogen
    CD299-transfected 300.19 pre-B cell line
    Klon
    HLy9-25
    Isotyp
    IgG1
    Top Product
    Discover our top product CD229 Primärantikörper
  • Applikationshinweise
    Functional application: Regulation of activation,
    Flow cytometry: Recommended dilution: 6-10 μg/mL, positive control: peripheral blood lymphocytes.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • de la Fuente, Tovar, Villamor, Zapater, Pizcueta, Campo, Bosch, Engel: "Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9." in: Blood, Vol. 97, Issue 11, pp. 3513-20, (2001) (PubMed).

  • Target
    LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
    Andere Bezeichnung
    CD229 (CD229 Produkte)
    Synonyme
    LY9 antikoerper, CD229 antikoerper, SLAMF3 antikoerper, hly9 antikoerper, mLY9 antikoerper, AI893573 antikoerper, Lgp100 antikoerper, Ly-9 antikoerper, T100 antikoerper, lymphocyte antigen 9 antikoerper, LY9 antikoerper, Ly9 antikoerper
    Hintergrund
    Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9
    Gen-ID
    4063
    UniProt
    Q9HBG7
    Pathways
    BCR Signaling
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