LY9 Antikörper
Kurzübersicht für LY9 Antikörper (ABIN1302441)
Target
Alle LY9 (CD229) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD229 Purified
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- CD299-transfected 300.19 pre-B cell line
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Isotyp
- IgG1
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Applikationshinweise
- Flow cytometry: Recommended dilution: 6 μg/mL, positive control: peripheral blood lymphocytes.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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Andere Bezeichnung
- CD229
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Hintergrund
- Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9
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Gen-ID
- 4063
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UniProt
- Q9HBG7
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Pathways
- BCR Signaling
Target
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