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LY9 Antikörper (Lymphocyte Antigen 9) (PE) Primary Antibody

CD229 Reaktivität: Human Func, ICC, FACS, IP, WB Wirt: Maus Monoclonal HLy9-25 PE
Pubmed (2 references)
Produktnummer ABIN1303129
$484.24
Zzgl. Versandkosten $45.00
100 tests
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle LY9 (CD229) Antikörper anzeigen
    LY9 (CD229)
    Reaktivität
    • 48
    • 15
    • 5
    Human
    Wirt
    • 42
    • 15
    • 1
    Maus
    Klonalität
    • 36
    • 22
    Monoklonal
    Konjugat
    • 32
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY9 Antikörper ist konjugiert mit PE
    Applikation
    • 27
    • 18
    • 16
    • 13
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
    Spezifität
    The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
    Kreuzreaktivität (Details)
    Human
    Immunogen
    CD299-transfected 300.19 pre-B cell line
    Klon
    HLy9-25
    Isotyp
    IgG1
  • Applikationshinweise
    The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    de la Fuente, Tovar, Villamor, Zapater, Pizcueta, Campo, Bosch, Engel: "Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9." in: Blood, Vol. 97, Issue 11, pp. 3513-20, (2001) (PubMed).

  • Target
    LY9 (CD229)
    Andere Bezeichnung
    CD229 (CD229 Produkte)
    Synonyme
    LY9, CD229, SLAMF3, hly9, mLY9, AI893573, Lgp100, Ly-9, T100, lymphocyte antigen 9, LY9, Ly9
    Hintergrund
    CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
    Pathways
    BCR Signaling
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