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CD40 Antikörper

CD40 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 1C10 unconjugated
Produktnummer ABIN2665994
  • Target Alle CD40 Antikörper anzeigen
    CD40
    Reaktivität
    • 192
    • 109
    • 21
    • 20
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 106
    • 101
    • 51
    • 6
    • 2
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 170
    • 92
    • 5
    Monoklonal
    Konjugat
    • 122
    • 25
    • 22
    • 18
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD40 Antikörper ist unkonjugiert
    Applikation
    • 153
    • 96
    • 63
    • 53
    • 32
    • 26
    • 19
    • 19
    • 16
    • 14
    • 13
    • 12
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marke
    Ultra-LEAF™
    Aufreinigung
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    Klon
    1C10
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD40 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Konservierungsmittel
    Azide free
    Handhabung
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD40
    Andere Bezeichnung
    CD40 (CD40 Produkte)
    Synonyme
    Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper
    Hintergrund
    CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
    Pathways
    NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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