TNFRSF13C Antikörper

Produktnummer ABIN2664464

Produktdetails anti-TNFRSF13C Antikörper

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF13C Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Blocking Reagent (BR)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 7H22-E16

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Andere Bezeichnung: CD268 (TNFRSF13C Produkte)

Synonyme: RGD1560810 antikoerper, TNFRSF13C antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, TNF receptor superfamily member 13C antikoerper, uncharacterized LOC746611 antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, TNFRSF13C antikoerper, Tnfrsf13c antikoerper, LOC746611 antikoerper

Hintergrund: BAFF (B cell-activating factor belonging to the TNF family) receptor (BAFF-R) is one of the three receptors that bind to BAFF. It is a type III transmembrane TNF receptor family member. BAFF-R is expressed at high levels in resting B cells and at lower levels in activated B cells, a small subset of activated/memory CD4+ T cells. It is a major mediator of BAFF dependent co-stimulatory response in peripheral B and T cells. It was reported that the mice expressing defective BAFF-R have disrupted B cell maturation. BAFF receptor appears to be particularly important for the regulation of normal B cell survival and maturation, as well as in the pathophysiology of aggressive B-cell malignancies and autoimmune diseases.

Pathways: NF-kappaB Signalweg