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CD40 Antikörper (FITC)

CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal 5C3 FITC

Produktnummer ABIN2567685

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
189

109

21

20

6

6

4

4

4

4

2

2

2

2

2

1
Human
Wirt
107

98

51

6

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
171

88

5
Monoklonal
Konjugat
121

24

21

19

12

8

7

4

4

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist konjugiert mit FITC
Applikation
149

96

63

53

32

26

19

19

16

14

13

13

8

6

5

5

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

5C3

Isotyp

IgG1 kappa

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CD40 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

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CD40 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 41-CD40 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reaktivität: Human FACS, IHC, St Wirt: Maus Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal HI40a FITC

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Synonyme

Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper

Hintergrund

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Gen-ID

958

UniProt

P25942

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints