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CTLA4 Antikörper (PE)
CTLA4
Reaktivität: Maus
FACS
Wirt: Hamster
Monoclonal
UC10-4F10-11
PE
Produktnummer ABIN2567247
Produktdetails anti-CTLA4 Antikörper (PE)
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Target
Alle CTLA4 Antikörper anzeigen
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reaktivität
Alle Reaktivitäten für CTLA4 Antikörper
Maus
Wirt
Alle Wirte für CTLA4 Antikörper
Hamster
Klonalität
Alle Klonalitäten für CTLA4 Antikörper
Monoklonal
Konjugat
Alle Konjugate für CTLA4 Antikörper
Dieser CTLA4 Antikörper ist konjugiert mit PE
Applikation
Alle Applikationen für CTLA4 Antikörper
Flow Cytometry (FACS)
Spezifität
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152.
Aufreinigung
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Klon
UC10-4F10-11
Isotyp
IgG
Top Product
Discover our top product CTLA4 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.2 mg/mL
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Lagerung
4 °C
Informationen zur Lagerung
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Details zu CTLA4
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Target
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Andere Bezeichnung
CD152 (CTLA4 Produkte )
Synonyme
CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
Hintergrund
The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
Gen-ID
12477
UniProt
P09793
Pathways
Cancer Immune Checkpoints
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