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CTLA4 Antikörper (PE)

CTLA4 Reaktivität: Maus FACS Wirt: Hamster Monoclonal UC10-4F10-11 PE
Produktnummer ABIN2567247
  • Target Alle CTLA4 Antikörper anzeigen
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reaktivität
    • 94
    • 64
    • 35
    • 5
    • 4
    Maus
    Wirt
    • 59
    • 50
    • 18
    • 12
    • 1
    • 1
    Hamster
    Klonalität
    • 84
    • 54
    • 2
    Monoklonal
    Konjugat
    • 63
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTLA4 Antikörper ist konjugiert mit PE
    Applikation
    • 85
    • 64
    • 51
    • 35
    • 19
    • 14
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152.
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Klon
    UC10-4F10-11
    Isotyp
    IgG
    Top Product
    Discover our top product CTLA4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Andere Bezeichnung
    CD152 (CTLA4 Produkte)
    Synonyme
    CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
    Hintergrund
    The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
    Gen-ID
    12477
    UniProt
    P09793
    Pathways
    Cancer Immune Checkpoints
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