CTLA4 Antikörper (AA 36-161)
-
- Target Alle CTLA4 Antikörper anzeigen
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
-
Bindungsspezifität
- AA 36-161
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CTLA4 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. coli.
- Klon
- 8B3F8
- Isotyp
- IgG1
- Top Product
- Discover our top product CTLA4 Primärantikörper
-
-
- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
-
- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Andere Bezeichnung
- CD152 (CTLA4 Produkte)
- Synonyme
- CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
- Hintergrund
-
Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Aliases: CTLA4, CD, GSE, GRD4, ALPS5, CTLA-4, IDDM12, CELIAC3
- Molekulargewicht
- 24.6 kDa
- Gen-ID
- 1493
- HGNC
- 1493
- Pathways
- Cancer Immune Checkpoints
-