Rekombinanter CTLA4 Antikörper (C-Term)
Kurzübersicht für Rekombinanter CTLA4 Antikörper (C-Term) (ABIN7795650)
Target
Alle CTLA4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Rabbit anti-CTLA4 Recombinant Monoclonal Antibody [BLR257L] - BSA-Free
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Aufreinigung
- Purified
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Immunogen
- Between 173 and C-terminus
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Andere Bezeichnung
- CTLA4
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Hintergrund
- CTLA4 is a member of the immunoglobulin superfamily and is an inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16410].
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Gen-ID
- 1493
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UniProt
- P16410
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Pathways
- Cancer Immune Checkpoints
Target
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