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CTLA4 Produkte

(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].

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Ausgewählte CTLA4 Kategorien

CTLA4 Antikörper

High quality antibodies with extensive validation data.

CTLA4 ELISA Kits

Reliable ELISA kits for a wide range of species.

CTLA4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CTLA4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (4)
  • (4)
Kat. Nr. ABIN1981896
Menge 100 tests
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN514751
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, IP, ICC, IHC (fro)
Validierungen
  • (4)
  • (3)
Kat. Nr. ABIN2749015
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene CTLA4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966262
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955276
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN3199209
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CTLA4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (6)
Kat. Nr. ABIN7274436
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (7)
Kat. Nr. ABIN6961090
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7274435
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CTLA4 Produkten

Krebs, Trzeciak, Zimmer, Özistanbullu, Mitzel-Rink, Meissner, Grabbe, Loquai, Tuettenberg: "Immune signature as predictive marker for response to checkpoint inhibitor immunotherapy and overall survival in melanoma." in: Cancer medicine, (2021) (PubMed).

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Wang, Li, Fan, Wang, Zhang, Zhang, Han, Lv, Liu: "Circulating CTLA-4 levels and CTLA4 polymorphisms associate with disease condition and progression and hepatocellular carcinoma patients' survival in chronic hepatitis B virus infection." in: International immunopharmacology, Vol. 82, pp. 106377, (2020) (PubMed).

Simons, Lim, Carter, Wagner, Wayham, Adler, Johnson: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).

Okada, Kajiya, Omata, Matsumoto, Sato, Kobayashi, Nakamura, Kaneko, Nakamura, Koyama, Sudo, Shin, Okamoto, Watanabe, Tachibana, Hirose, Saito, Takai, Matsumoto, Nakamura, Okabe, Miyamoto, Tanaka: "CTLA4-Ig Directly Inhibits Osteoclastogenesis by Interfering With Intracellular Calcium Oscillations in Bone Marrow Macrophages." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).

Ganesan, Moon, Barakat: "Revealing the atomistic details behind the binding of B7-1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study." in: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 12, pp. 2764-2778, (2019) (PubMed).

Ehlerding, Lee, Jiang, Ferreira, Zahm, Huang, Engle, McNeel, Cai: "Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models." in: American journal of cancer research, Vol. 9, Issue 1, pp. 53-63, (2019) (PubMed).

Galstyan, Markman, Shatalova, Chiechi, Korman, Patil, Klymyshyn, Tourtellotte, Israel, Braubach, Ljubimov, Mashouf, Ramesh, Grodzinski, Penichet, Black, Holler, Sun, Ding, Ljubimov, Ljubimova: "Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy." in: Nature communications, Vol. 10, Issue 1, pp. 3850, (2019) (PubMed).

Gonzalez-Nieto, Castro, Bischof, Shin, Ricciardi, Bailey, Dang, Pedreño-Lopez, Magnani, Ejima, Allison, Gil, Evans, Rakasz, Lifson, Desrosiers, Martins: "Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques." in: PLoS pathogens, Vol. 15, Issue 9, pp. e1008015, (2019) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Synonyme und alternative Namen zu CTLA4

cytotoxic T-lymphocyte associated protein 4 (CTLA4), cytotoxic T-lymphocyte-associated protein 4 (Ctla4), CD, CD152, Cd152, CELIAC3, CTLA-4, Ctla-4, CTLA4, GRD4, GSE, IDDM12, Ly-56, sCTLA4

Bezeichner auf Proteinebene für CTLA4

  • cytotoxic T-lymphocyte-associated protein 4 precursor
  • CD152 protein
  • cytotoxic T-lymphocyte protein 4
  • cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM
  • cytotoxic T-lymphocyte-associated protein 4
  • costimulatory molecule B7 receptor
  • cytotoxic T lymphocyte-associated antigen 4
  • CD152 antigen
  • cytotoxic T-lymphocyte-associated antigen 4
  • CD152 isoform
  • celiac disease 3
  • cytotoxic T lymphocyte associated antigen 4 short spliced form
  • cytotoxic T-lymphocyte antigen 4
  • cytotoxic T-lymphocyte-associated serine esterase-4
  • ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
  • soluble form
  • transmembrane form
  • CTLA-4
  • cytotoxic T lymphocyte-associated protein 4
  • costimulatory molecule B7 receptor CD152
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