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CTCFL Produkte

(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].

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Ausgewählte CTCFL Kategorien

CTCFL Antikörper

High quality antibodies with extensive validation data.

CTCFL ELISA Kits

Reliable ELISA kits for a wide range of species.

CTCFL Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CTCFL Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7172781
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (6)
  • (1)
Kat. Nr. ABIN129668
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ChIP-seq, ChIP
Validierungen
  • (2)
Kat. Nr. ABIN6971455
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CTCFL ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965537
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN5594143
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6225336
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CTCFL Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122188
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350632
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3130794
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CTCFL Produkten

Janssen, Moscona, Elchebly, Papadakis, Redpath, Wang, Rubin, van Kempen, Spatz: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." in: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).

Freitas, Malheiros, Stávale, Biassi, Zamunér, de Souza Begnami, Soares, Vettore: "Expression of cancer/testis antigens is correlated with improved survival in glioblastoma." in: Oncotarget, Vol. 4, Issue 4, pp. 636-46, (2013) (PubMed).

Rosa-Garrido, Ceballos, Alonso-Lecue, Abraira, Delgado, Gandarillas: "A cell cycle role for the epigenetic factor CTCF-L/BORIS." in: PLoS ONE, Vol. 7, Issue 6, pp. e39371, (2012) (PubMed).

Macaluso, Caracciolo, Rizzo, Sun, Montanari, Russo, Bellipanni, Khalili, Giordano: "Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 9, pp. 1841-50, (2012) (PubMed).

Fiorentino, Macaluso, Miranda, Montanari, Russo, Bagella, Giordano: "CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 225-33, (2011) (PubMed).

Jones, Ogunkolade, Szary, Aarum, Mumin, Patel, Pieri, Sheer: "Widespread expression of BORIS/CTCFL in normal and cancer cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22399, (2011) (PubMed).

Bhan, Negi, Shao, Glazer, Chuang, Gaykalova, Sun, Sidransky, Ha, Califano: "BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 13, pp. 4267-76, (2011) (PubMed).

Hines, Bazarov, Mukhopadhyay, Yaswen: "BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas." in: PLoS ONE, Vol. 5, Issue 3, pp. e9738, (2010) (PubMed).

Monk, Hitchins, Hawes: "Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development." in: Molecular human reproduction, Vol. 14, Issue 6, pp. 347-55, (2008) (PubMed).

Dougherty, Ichim, Liu, Reznik, Min, Ghochikyan, Agadjanyan, Reznik: "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS." in: Biochemical and biophysical research communications, Vol. 370, Issue 1, pp. 109-12, (2008) (PubMed).

Synonyme und alternative Namen zu CTCFL

CCCTC-binding factor like (CTCFL), CCCTC-binding factor (zinc finger protein)-like (Ctcfl), CCCTC-binding factor like (Ctcfl), BORIS, Boris, CT27, CTCF-T, CTCFL, dJ579F20.2, HMGB1L1, OTTMUSG00000016680

Bezeichner auf Proteinebene für CTCFL

  • BORIS-like protein
  • CTCF paralog
  • CTCF-like protein
  • HMG-1L1
  • brother of the regulator of imprinted sites
  • cancer/testis antigen 27
  • putative high mobility group protein 1-like 1
  • putative high mobility group protein B1-like 1
  • transcriptional repressor CTCFL
  • zinc finger protein CTCF-T
  • CCCTC-binding factor (zinc finger protein)-like
  • CCCTC-binding factor-like protein
  • BORIS
  • Brother of the regulator of imprinted sites
  • likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL)
  • brother of regulator of imprinted sites
  • transcriptional repressor CTCFL-like
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