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CTNNA1 Produkte

(Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

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Ausgewählte CTNNA1 Kategorien

CTNNA1 Antikörper

High quality antibodies with extensive validation data.

CTNNA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CTNNA1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CTNNA1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (7)
Kat. Nr. ABIN6260492
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP
Validierungen
  • (8)
Kat. Nr. ABIN6139202
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN7261582
Menge 200 μL
Datenblatt Datenblatt

Empfohlene CTNNA1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954435
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380986
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Pig
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN778448
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CTNNA1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350658
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350660
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3091997
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CTNNA1 Produkten

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).

Tripathi, Popescu, Zimonjic: "DLC1 interaction with ?-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity." in: Molecular and cellular biology, Vol. 32, Issue 11, pp. 2145-59, (2012) (PubMed).

Bajpai, Feng, Krishnamurthy, Longmore, Wirtz: "Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells." in: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18252-9, (2009) (PubMed).

Yamada, Pokutta, Drees, Weis, Nelson: "Deconstructing the cadherin-catenin-actin complex." in: Cell, Vol. 123, Issue 5, pp. 889-901, (2005) (PubMed).

Drees, Pokutta, Yamada, Nelson, Weis: "Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly." in: Cell, Vol. 123, Issue 5, pp. 903-15, (2005) (PubMed).

Hwang, Yu, Ryu, Jeon, Yoo, Eom, Chun: "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12758-65, (2005) (PubMed).

Lynch, Grady, Suriano, Huntsman: "Gastric cancer: new genetic developments." in: Journal of surgical oncology, Vol. 90, Issue 3, pp. 114-33; discussion 133, (2005) (PubMed).

Lin, Wu, Li, Wu, Zheng: "Prognostic and clinicopathological features of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin and cyclin D1 expression in human esophageal squamous cell carcinoma." in: World journal of gastroenterology, Vol. 10, Issue 22, pp. 3235-9, (2005) (PubMed).

Katafiasz, Nieman, Wheelock, Johnson: "Characterization of cadherin-24, a novel alternatively spliced type II cadherin." in: The Journal of biological chemistry, Vol. 278, Issue 30, pp. 27513-9, (2003) (PubMed).

Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

Synonyme und alternative Namen zu CTNNA1

catenin alpha 1 (CTNNA1), catenin (cadherin associated protein), alpha 1 (Ctnna1), catenin alpha 1 (Ctnna1), alpha Catenin (alpha-Cat), alpha Catenin (Dgri\alpha-Cat), catenin alpha-1 (Tsp_10127), catenin (cadherin-associated protein), alpha 1 (ctnna1), catenin alpha 1 S homeolog (ctnna1.S), 2010010M04Rik, a-Cat, a-cat, AA517462, AI988031, alpha-CAT, alpha-cat, Alpha-Cat, alpha-catenin, alpha-ctn, alphaCAT, alphaCat, alphacat, CAP102, cap102, Catna1, catna1, CG17947, CT39986, ctnna, ctnna1, Dalpha-Cat, Dalpha-cat, DalphaC, Dalphacat, DgriGH19548, dgri_GLEANR_3829, Dmcatp, Dmel\\CG17947, GH19548

Bezeichner auf Proteinebene für CTNNA1

  • alpha E-catenin
  • alpha-E-catenin
  • alpha-catenin
  • alphaE-catenin
  • cadherin-associated protein,102kDa
  • catenin alpha-1
  • renal carcinoma antigen NY-REN-13
  • a-catenin
  • 102 kDa cadherin-associated protein
  • CAP102
  • alpha E catenin
  • alpha(E)-catenin
  • cadherin associated protein
  • catenin alpha 1
  • catenin (cadherin associated protein), alpha 1
  • catenin, alpha 1
  • CG17947-PA
  • D-alpha-catenin
  • Dalpha-Catenin
  • Dalpha-cadherin
  • DalphaCatenin
  • alpha catenin
  • alpha-Cat-PA
  • alpha-Catenin
  • alphaCatenin
  • catenin alpha 1 subunit
  • DgriGH19548-PA
  • Dgrialpha-Cat-PA
  • GH19548-PA
  • catenin (cadherin-associated protein), alpha 1, 102kDa
  • catenin alpha-1-like
  • [a]E-catenin
  • catenin alpha 1 S homeolog
  • LOW QUALITY PROTEIN: catenin alpha-1
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