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CTLA4 Antikörper (PE)

CTLA4 Reaktivität: Human FACS Wirt: Maus Monoclonal BNI3 PE
Produktnummer ABIN2567241
  • Target Alle CTLA4 Antikörper anzeigen
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reaktivität
    • 94
    • 64
    • 35
    • 5
    • 4
    Human
    Wirt
    • 59
    • 50
    • 18
    • 12
    • 1
    • 1
    Maus
    Klonalität
    • 84
    • 54
    • 2
    Monoklonal
    Konjugat
    • 63
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTLA4 Antikörper ist konjugiert mit PE
    Applikation
    • 85
    • 64
    • 51
    • 35
    • 19
    • 14
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4).
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Klon
    BNI3
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CTLA4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Andere Bezeichnung
    CD152 (CTLA4 Produkte)
    Synonyme
    CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
    Hintergrund
    The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.
    Gen-ID
    1493
    UniProt
    P16410
    Pathways
    Cancer Immune Checkpoints
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