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ATF2 Antikörper (pSer472)
ATF2
Reaktivität: Human, Maus, Ratte
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2567048
Produktdetails anti-ATF2 Antikörper
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Target
Alle ATF2 Antikörper anzeigen
ATF2
(Activating Transcription Factor 2 (ATF2))
Bindungsspezifität
Alle Epitope für ATF2 Antikörper
pSer472
Reaktivität
Alle Reaktivitäten für ATF2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für ATF2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für ATF2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für ATF2 Antikörper
Dieser ATF2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ATF2 Antikörper
Immunohistochemistry (IHC)
Spezifität
The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472.
Aufreinigung
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
ATF-2 (phospho Ser472) antibody was raised against a peptide sequence around phosphorylation site of Serine 472 (E-A-V (p)-A-T) derived from Human ATF-2.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store antibody at -20°C for up to one year.
Details zu ATF2
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Target
ATF2
(Activating Transcription Factor 2 (ATF2))
Andere Bezeichnung
ATF-2 (ATF2 Produkte )
Synonyme
CRE-BP1 antikoerper, CREB2 antikoerper, HB16 antikoerper, TREB7 antikoerper, CG12850 antikoerper, CG3749 antikoerper, dATF-2 antikoerper, DmelCG30420 antikoerper, CG30420 antikoerper, CHN1 antikoerper, Atf-2 antikoerper, CRE-BP antikoerper, Creb2 antikoerper, D130078H02Rik antikoerper, D18875 antikoerper, Tg(Gzma-Klra1)7Wum antikoerper, mXBP antikoerper, atf2-A antikoerper, atf2l antikoerper, activating transcription factor 2 antikoerper, Activating transcription factor-2 antikoerper, activating transcription factor 2 S homeolog antikoerper, ATF2 antikoerper, Atf-2 antikoerper, Atf2 antikoerper, atf2.S antikoerper, atf2 antikoerper
Hintergrund
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
Molekulargewicht
54 kDa
Gen-ID
1386
NCBI Accession
NP_001243019
UniProt
P15336
Pathways
MAPK Signalweg , RTK Signalweg , Thyroid Hormone Synthesis , Activation of Innate immune Response , Chromatin Binding , Myometrial Relaxation and Contraction , Synaptic Membrane , Tube Formation , Toll-Like Receptors Cascades
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