CD14 Antikörper
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- Target Alle CD14 Antikörper anzeigen
- CD14
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD14 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Aufreinigung
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Antibody is purified by protein G affinity chromatography and resuspended in PBS with 0.2%BSA,
0.09% sodium azide. No reconstitution is necessar Concentration is 0.4mg/ml. - Immunogen
- Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).
- Klon
- 5A3H5D5(FC)-5A3B11B5
- Isotyp
- IgG1
- Top Product
- Discover our top product CD14 Primärantikörper
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- Applikationshinweise
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IHC:Dilution 1:200 - 1:400
ELISA:Determining optimal working dilutions by titration test.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS containing 0.03 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- CD14 monoclonal antibody can be stored at -20 °C, stable for one year.
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- Target
- CD14
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- Synonyme
- CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
- Hintergrund
- CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
- Gen-ID
- 929
- UniProt
- P08571
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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