CDKN2B Antikörper

Produktnummer ABIN2463682

Produktdetails anti-CDKN2B Antikörper

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDKN2B.

Anwendungsinformationen

Applikationshinweise: CDKN2B antibody can be used for detection of CDKN2B by ELISA at 1:2500. CDKN2B antibody can be used for detection of CDKN2B by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDKN2B antibody at -20 °C.

Details zu CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Andere Bezeichnung: CDKN2B (CDKN2B Produkte)

Synonyme: p14-INK4b antikoerper, cdk4l antikoerper, ink4b antikoerper, mts2 antikoerper, p15 antikoerper, p15ink4b antikoerper, tp15 antikoerper, CDK4I antikoerper, INK4B antikoerper, MTS2 antikoerper, P15 antikoerper, TP15 antikoerper, p15INK4b antikoerper, AV083695 antikoerper, INK4b antikoerper, p15(INK4b) antikoerper, CDKN2A antikoerper, cyclin dependent kinase inhibitor 2B antikoerper, Cyclin-dependent kinase 4 inhibitor B antikoerper, cyclin-dependent kinase inhibitor 2B antikoerper, cyclin-dependent kinase inhibitor 2B L homeolog antikoerper, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antikoerper, CDKN2B antikoerper, cdn2b antikoerper, cdkn2b antikoerper, cdkn2b.L antikoerper, Cdkn2b antikoerper

Hintergrund: CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.

Molekulargewicht: 15 kDa

Gen-ID: 1030

NCBI Accession: NP_004927

UniProt: P42772

Pathways: Zellzyklus, Mitotic G1-G1/S Phases