Cadherin 4 Antikörper

Produktnummer ABIN2458919

Produktdetails anti-Cadherin 4 Antikörper

Target: Cadherin 4 (CDH4)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH4.

Anwendungsinformationen

Applikationshinweise: CDH4 antibody can be used for detection of CDH4 by ELISA at 1:62500. CDH4 antibody can be used for detection of CDH4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDH4 antibody at -20 °C.

Details zu Cadherin 4

Target: Cadherin 4 (CDH4)

Andere Bezeichnung: CDH4 (CDH4 Produkte)

Synonyme: cad4 antikoerper, rcad antikoerper, R-cadherin antikoerper, cadherin-4 antikoerper, AW120700 antikoerper, R-Cadh antikoerper, Rcad antikoerper, Cdh4l antikoerper, zgc:136316 antikoerper, CAD4 antikoerper, RCAD antikoerper, cadherin 4 antikoerper, cadherin 4, type 1, R-cadherin (retinal) antikoerper, Cadherin-4 antikoerper, cdh4 antikoerper, Cdh4 antikoerper, CDH4 antikoerper, cdh-4 antikoerper

Hintergrund: CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 82 kDa

Gen-ID: 1002

NCBI Accession: NP_001785

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size