Cadherin 4 Antikörper (N-Term)
Kurzübersicht für Cadherin 4 Antikörper (N-Term) (ABIN356865)
Target
Alle Cadherin 4 (CDH4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 182-211, N-Term
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Spezifität
- This antibody is specific to CDH4 (N-term).
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Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- KLH conjugated synthetic peptide between 182~211 amino acids from the N-terminal region of human CDH4 . Genename: CDH4
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Cadherin 4 (CDH4)
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Andere Bezeichnung
- Cadherin-4
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Hintergrund
- CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.Synonyms: CDH4, Cadherin R, R Cadherin, R-CAD, Retinal Cadherin
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Molekulargewicht
- 100281 Da
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Gen-ID
- 1002, 9606
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UniProt
- P55283
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Pathways
- Cell-Cell Junction Organization, Regulation of Cell Size
Target
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