Cadherin 4 Antikörper (CDH4) (AA 22-201)

Details for Product anti-CDH4 Antibody No. ABIN967954, Anbieter: Anmelden zum Anzeigen
Antigen
  • cad4
  • rcad
  • R-cadherin
  • cadherin-4
  • AW120700
  • R-Cadh
  • Rcad
  • Cdh4l
  • zgc:136316
  • CAD4
  • RCAD
  • cadherin 4
  • cadherin 4, type 1, R-cadherin (retinal)
  • Cadherin-4
  • cdh4
  • Cdh4
  • CDH4
  • cdh-4
Epitop
AA 22-201
16
13
12
6
4
4
3
3
2
2
2
2
1
1
Reaktivität
Maus, Ratte (Rattus)
86
38
27
2
2
2
2
2
1
1
Wirt
Maus
69
17
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Cadherin 4 Antikörper ist unkonjugiert
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
63
37
29
27
20
15
13
9
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Mouse R-Cadherin aa. 22-201
Klon 48-R
Isotyp IgG2a, kappa
Kreuzreaktivität Ratte (Rattus)
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Andere Bezeichnung R-Cadherin (CDH4 Antibody Abstract)
Hintergrund R-Cadherin was first isolated from chicken retina, but was subsequently shown to be present and highly conserved in a variety of tissues from several different species. A 913 amino acid polypeptide, R-Cadherin is highly homologous to Cadherin-4, but is most closely related to another family member, N-Cadherin. In experiments using chimeric L cells expressing chicken or mouse Cadherins, those cells expressing mouse or chicken R-Cadherin were able to aggregate with each other as well as with cells expressing N-Cadherin. However, there was no aggregation of R-Cadherin expressing cells, with P- or E-Cadherin expressing cells. This suggests that the roles of specific cadherins are conserved among types in the determination of heterogenous cell segregation and distribution during tissue morphogenesis and maintenance.
Molekulargewicht 100 kDa
Pathways Cell-Cell Junction Organization, Regulation of Cell Size
Kommentare

Related Products: ABIN968545, ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20°C.
Bilder des Herstellers
Western Blotting (WB) image for anti-Cadherin 4 (CDH4) (AA 22-201) antibody (ABIN967954) Western blot analysis of R-Cadherin on rat brain lysate. Lane 1: 1:500, lane 2: 1:100...
 image for anti-Cadherin 4 (CDH4) (AA 22-201) antibody (ABIN967954) anti-Cadherin 4 (CDH4) (AA 22-201) antibody (Image 2)
Western Blotting (WB) image for anti-Cadherin 4 (CDH4) (AA 22-201) antibody (ABIN967954) anti-Cadherin 4 (CDH4) (AA 22-201) antibody (Image 3)
Produkt verwendet in: Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, 1995 (PubMed).

Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, 1994 (PubMed).

Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, 1994 (PubMed).

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