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Cadherin 4 Antikörper (N-Term)

CDH4 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB13654 unconjugated
Produktnummer ABIN388148
  • Target Alle Cadherin 4 (CDH4) Antikörper anzeigen
    Cadherin 4 (CDH4)
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-203, N-Term
    Reaktivität
    • 64
    • 23
    • 11
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 59
    • 6
    • 1
    Kaninchen
    Klonalität
    • 61
    • 5
    Polyklonal
    Konjugat
    • 25
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cadherin 4 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 25
    • 22
    • 18
    • 13
    • 13
    • 13
    • 9
    • 9
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the N-terminal region of human CDH4.
    Klon
    RB13654
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Li, Takai, Yuge, Furukawa, Tsuno, Tsukamoto, Kong, Moriyama, Narahara: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." in: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).

  • Target
    Cadherin 4 (CDH4)
    Andere Bezeichnung
    CDH4 (CDH4 Produkte)
    Synonyme
    cad4 antikoerper, rcad antikoerper, R-cadherin antikoerper, cadherin-4 antikoerper, AW120700 antikoerper, R-Cadh antikoerper, Rcad antikoerper, Cdh4l antikoerper, zgc:136316 antikoerper, CAD4 antikoerper, RCAD antikoerper, cadherin 4 antikoerper, cadherin 4, type 1, R-cadherin (retinal) antikoerper, Cadherin-4 antikoerper, cdh4 antikoerper, Cdh4 antikoerper, CDH4 antikoerper, cdh-4 antikoerper
    Hintergrund
    CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
    Molekulargewicht
    100281
    Gen-ID
    1002
    NCBI Accession
    NP_001239267, NP_001239268, NP_001785
    UniProt
    P55283
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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