IL-6 Receptor Antikörper (Internal Region)

Produktnummer ABIN185570

Produktdetails anti-IL-6 Receptor Antikörper

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IL-6 Receptor Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: IL6R / CD126 (isoform 1)

Sequenz: DNTSSHNRPD ARD

Spezifität: This antibody is expected to recognise isoform 1 only (NP_000556.1)

Homologie: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Recent

Immunogen: Peptide with sequence C-DNTSSHNRPDARD, from the internal region of the protein sequence according to NP_000556.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

DS WB Results: Preliminary experiments gave an approx 26-28 kDa band in Human Bone Marrow and Tonsil lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 51.5 kDa according to NP_000556.1. The 26-28 kDa band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Peptide ELISA: antibody detection limit dilution 1:8000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Andere Bezeichnung: IL6R / CD126 (IL6R Produkte)

Synonyme: IL6R antikoerper, il-6ra antikoerper, CD126 antikoerper, IL-6R-1 antikoerper, IL-6RA antikoerper, IL6Q antikoerper, IL6RA antikoerper, IL6RQ antikoerper, gp80 antikoerper, IL6R1 antikoerper, Il6ra antikoerper, IL-6Ralpha antikoerper, IL-6R antikoerper, Il6r antikoerper, interleukin 6 receptor antikoerper, interleukin 6 receptor, alpha antikoerper, IL6R antikoerper, il6r antikoerper, Il6r antikoerper, Il6ra antikoerper

Hintergrund: IL6R, interleukin 6 receptor , HGNC:6019, CD126, IL-6R-1, IL-6R-alpha, IL6RA, MGC104991 , CD126 antigen, interleukin 6 receptor alpha subunit

Gen-ID: 3570

NCBI Accession: NP_000556

Pathways: JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints