CD11c Antikörper (N-Term)

Produktnummer ABIN2843834

Produktdetails anti-CD11c Antikörper

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Bindungsspezifität: AA 246-274, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11c Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c.

Klon: 428CT12-2-6-4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:100~500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ITGAX/CD11c Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Andere Bezeichnung: ITGAX/CD11c (ITGAX Produkte)

Synonyme: CD11C antikoerper, SLEB6 antikoerper, RGD1561123 antikoerper, AI449405 antikoerper, Cd11c antikoerper, Cr4 antikoerper, N418 antikoerper, integrin subunit alpha X antikoerper, integrin alpha X antikoerper, ITGAX antikoerper, Itgax antikoerper

Hintergrund: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Molekulargewicht: 127829

Gen-ID: 3687

NCBI Accession: NP_000878

UniProt: P20702

Pathways: Komplementsystem, Activated T Cell Proliferation, Integrin Complex