GLUT4 Antikörper (AA 498-509)

Produktnummer ABIN1492810

Produktdetails anti-GLUT4 Antikörper

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Bindungsspezifität: AA 498-509

Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Pferd, Affe, Fledermaus, Hamster

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GLUT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human SLC2A4 / GLUT4.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Panda, Bat, Rabbit, Horse, Pig, Opossum (100%) Bovine (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-TELEYLGPDEND from the C-terminus of human SLC2A4 / GLUT4 (NP_001033.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Panda, Bat, Rabbit, Horse, Pig, Opossum (100%), Bovine (92%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 45kD band observed in Mouse and Rat Heart lysates (calculated MW of 54.8kD according to Human NP_001033.1 and Mouse NP_033230.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Fischer et al, J Biol Chem. 1997 Mar 14,272(11):7085-92., PMID: 9054401). Recommended concentration: 0.3-1 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Andere Bezeichnung: SLC2A4 / GLUT4 / GLUT-4 (SLC2A4 Produkte)

Synonyme: GLUT4 antikoerper, Glut-4 antikoerper, Glut4 antikoerper, glut4 antikoerper, slc2a4 antikoerper, SLC2A4 antikoerper, solute carrier family 2 member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antikoerper, SLC2A4 antikoerper, Slc2a4 antikoerper, GLUT4 antikoerper, slc2a4.L antikoerper

Hintergrund: Name/Gene ID: SLC2A4
Subfamily: Sugar transporter
Family: Transporter

Synonyms: SLC2A4, Glucose transporter 4, Glucose transporter GLUT4, GLUT4, GLUT-4

Gen-ID: 6517

NCBI Accession: NP_001033

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt