CD40 Antikörper (PE)
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- Target Alle CD40 Antikörper anzeigen
- CD40
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD40 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse CD40
- Immunogen
- mouse CD40-human IgG1 fusion protein
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD40 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/ml
- Lagerung
- 4 °C
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- Target
- CD40
- Andere Bezeichnung
- CD40 (CD40 Produkte)
- Synonyme
- Bp50 antikoerper, CDW40 antikoerper, TNFRSF5 antikoerper, p50 antikoerper, AI326936 antikoerper, GP39 antikoerper, HIGM1 antikoerper, IGM antikoerper, IMD3 antikoerper, T-BAM antikoerper, TRAP antikoerper, Tnfrsf5 antikoerper, TNFSF5 antikoerper, CD40 molecule antikoerper, CD40 antigen antikoerper, CD40 antikoerper, Cd40 antikoerper
- Hintergrund
- Anti-mouse monoclonal antibody (clone 3/23) reacts with CD40 which is ex- pressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal center formation, and generating B cell memory . Stimulat- ing cells with immobilized 3/23 mAb increases expression of CD86 (B7.2) on B cells 1,3 Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD The 3/23 clone is suitable for use in flow cytometry and acetone fixed frozen tissue sec- tions
- Pathways
- NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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